Systems analysis of protective immune responses to RTS,S malaria vaccination in humans
Systems analysis of protective immune responses to RTS,S malaria vaccination in humans
About this item
Full title
Author / Creator
Kazmin, Dmitri , Nakaya, Helder I. , Lee, Eva K. , Johnson, Matthew J. , van der Most, Robbert , van den Berg, Robert A. , Ballou, W. Ripley , Jongert, Erik , Wille-Reece, Ulrike , Ockenhouse, Christian , Aderem, Alan , Zak, Daniel E. , Sadoff, Jerald , Hendriks, Jenny , Wrammert, Jens , Ahmed, Rafi and Pulendran, Bali
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
RTS,S is an advanced malaria vaccine candidate and confers significant protection against Plasmodium falciparum infection in humans. Little is known about the molecular mechanisms driving vaccine immunity. Here, we applied a systems biology approach to study immune responses in subjects receiving three consecutive immunizations with RTS,S (RRR), or...
Alternative Titles
Full title
Systems analysis of protective immune responses to RTS,S malaria vaccination in humans
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5338562
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5338562
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1621489114
