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Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5347571

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

About this item

Full title

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1857-E1865

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Voltage-gated sodium channels (Navs) play crucial roles in excitable cells. Although vertebrate Nav function has been extensively studied, the detailed structural basis for voltage-dependent gating mechanisms remain obscure. We have assessed the structural changes of the Nav voltage sensor domain using lanthanide-based resonance energy transfer (LR...

Alternative Titles

Full title

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5347571

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5347571

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1700453114

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