SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5...
SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis
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Author / Creator
Liu, Kuancan , Xie, Fuan , Gao, Anding , Zhang, Rui , Zhang, Long , Xiao, Zhangwu , Hu, Qiong , Huang, Weifeng , Huang, Qiaojia , Lin, Baoshun , Zhu, Jian , Wang, Haikun , Que, Jianwen and Lan, Xiaopeng
Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
High levels of SOX2 protein are correlated with increased dissemination of breast cancer. However, the underlying molecular mechanisms are not fully understood.
In this study we investigate the role of SOX2 in breast cancer metastasis using multiple in vitro and in vivo assays including cell culture, shRNA-mediated knockdown, wound healing, colo...
Alternative Titles
Full title
SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5348847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5348847
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-017-0632-9