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Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension

Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5355711

Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension

About this item

Full title

Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension

Publisher

Greece: D.A. Spandidos

Journal title

Molecular medicine reports, 2017-01, Vol.15 (1), p.160-168

Language

English

Formats

Publication information

Publisher

Greece: D.A. Spandidos

More information

Scope and Contents

Contents

Galectin-3 (Gal-3) is a β-galactoside-binding lectin, which is important in inflammation, fibrosis and heart failure. The present study aimed to investigate the role and mechanism of Gal-3 in hypoxia-induced pulmonary arterial hypertension (PAH). Male C57BL/6J and Gal-3−/− mice were exposed to hypoxia, then the right ventricular systolic pressure (...

Alternative Titles

Full title

Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5355711

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5355711

Other Identifiers

ISSN

1791-2997

E-ISSN

1791-3004

DOI

10.3892/mmr.2016.6020

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