Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ
Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The proinflammatory cytokine IL-36γ is highly expressed in epithelial cells and is a pivotal mediator of epithelial inflammation. In particular, IL-36γ is strongly associated with the inflammatory skin disease psoriasis. As with other IL-1 cytokines, IL-36γ is expressed as an inactive precursor and must be processed by specific proteases to become...
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Full title
Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5380102
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5380102
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1620954114
