Stop pulling my strings — what telomeres taught us about the DNA damage response
Stop pulling my strings — what telomeres taught us about the DNA damage response
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Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Key Points
Telomeres are essential nucleoprotein structures that protect chromosome ends. In mammals, telomeres are composed of TTAGGG repeats, which are bound by a protein complex termed shelterin.
Cell divisions lead to the progressive erosion of telomeric repeats. When telomeres become too short to recruit the shelterin complex, they becom...
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Full title
Stop pulling my strings — what telomeres taught us about the DNA damage response
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5385261
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5385261
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm.2016.43
