CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Rece...
CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors
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Author / Creator
Ishibashi, Masayuki , Neri, Shinya , Hashimoto, Hiroko , Miyashita, Tomoyuki , Yoshida, Tatsuya , Nakamura, Yuka , Udagawa, Hibiki , Kirita, Keisuke , Matsumoto, Shingo , Umemura, Shigeki , Yoh, Kiyotaka , Niho, Seiji , Tsuboi, Masahiro , Masutomi, Kenkichi , Goto, Koichi , Ochiai, Atsushi and Ishii, Genichiro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cancer associated fibroblasts (CAFs) play important roles in the chemotherapeutic process, especially through influencing the resistance of tumor cells to molecular targeted therapy. Here we report the existence of a special subpopulation of patient-specific-CAFs that augment the sensitivity of
EGFR
gene mutation-positive lung cancer to the E...
Alternative Titles
Full title
CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5399371
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5399371
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep46662
