Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell...
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
About this item
Full title
Author / Creator
Carrington, Emma M , Zhan, Yifan , Brady, Jamie L , Zhang, Jian-Guo , Sutherland, Robyn M , Anstee, Natasha S , Schenk, Robyn L , Vikstrom, Ingela B , Delconte, Rebecca B , Segal, David , Huntington, Nicholas D , Bouillet, Philippe , Tarlinton, David M , Huang, David CS , Strasser, Andreas , Cory, Suzanne , Herold, Marco J and Lew, Andrew M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Survival of various immune cell populations has been proposed to preferentially rely on a particular anti-apoptotic BCL-2 family member, for example, naive T cells require BCL-2, while regulatory T cells require MCL-1. Here we examined the survival requirements of multiple immune cell subsets
in vitro
and
in vivo
, using both genetic an...
Alternative Titles
Full title
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
Authors, Artists and Contributors
Author / Creator
Zhan, Yifan
Brady, Jamie L
Zhang, Jian-Guo
Sutherland, Robyn M
Anstee, Natasha S
Schenk, Robyn L
Vikstrom, Ingela B
Delconte, Rebecca B
Segal, David
Huntington, Nicholas D
Bouillet, Philippe
Tarlinton, David M
Huang, David CS
Strasser, Andreas
Cory, Suzanne
Herold, Marco J
Lew, Andrew M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5423112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5423112
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2017.30
