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Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation

Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5443899

Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation

About this item

Full title

Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory and critical care medicine, 2017-05, Vol.195 (10), p.1321-1332

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

The release of eosinophil granule proteins in the lungs of patients with asthma has been dogmatically linked with lung remodeling and airway hyperresponsiveness. However, the demonstrated inability of established mouse models to display the eosinophil degranulation occurring in human subjects has prevented a definitive in vivo test of this hypothes...

Alternative Titles

Full title

Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5443899

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5443899

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.201606-1129OC

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