In vivo genome editing and organoid transplantation models of colorectal cancer
In vivo genome editing and organoid transplantation models of colorectal cancer
About this item
Full title
Author / Creator
Roper, Jatin , Tammela, Tuomas , Cetinbas, Naniye Malli , Akkad, Adam , Roghanian, Ali , Rickelt, Steffen , Almeqdadi, Mohammad , Wu, Katherine , Oberli, Matthias , Sánchez-Rivera, Francisco , Park, Yoona , Liang, Xu , Eng, George , Taylor, Martin S. , Azimi, Roxana , Kedrin, Dmitriy , Neupane, Rachit , Beyaz, Semir , Sicinska, Ewa T. , Suarez, Yvelisse , Yoo, James , Chen, Lillian , Zukerberg, Lawrence , Katajisto, Pekka , Deshpande, Vikram , Bass, Adam , Tsichlis, Philip N. , Lees, Jacqueline , Langer, Robert , Hynes, Richard O. , Chen, Jianzhu , Bhutkar, Arjun J. , Jacks, Tyler and Yilmaz, Ömer H.
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
In vivo
interrogation of the function of genes implicated in tumorigenesis is limited by the need to generate and cross germline mutant mice. Here we describe approaches to model colorectal cancer (CRC) and metastasis that rely on
in situ
gene editing and orthotopic organoid transplantation in mice without cancer predisposing mutations. Au...
Alternative Titles
Full title
In vivo genome editing and organoid transplantation models of colorectal cancer
Authors, Artists and Contributors
Author / Creator
Tammela, Tuomas
Cetinbas, Naniye Malli
Akkad, Adam
Roghanian, Ali
Rickelt, Steffen
Almeqdadi, Mohammad
Wu, Katherine
Oberli, Matthias
Sánchez-Rivera, Francisco
Park, Yoona
Liang, Xu
Eng, George
Taylor, Martin S.
Azimi, Roxana
Kedrin, Dmitriy
Neupane, Rachit
Beyaz, Semir
Sicinska, Ewa T.
Suarez, Yvelisse
Yoo, James
Chen, Lillian
Zukerberg, Lawrence
Katajisto, Pekka
Deshpande, Vikram
Bass, Adam
Tsichlis, Philip N.
Lees, Jacqueline
Langer, Robert
Hynes, Richard O.
Chen, Jianzhu
Bhutkar, Arjun J.
Jacks, Tyler
Yilmaz, Ömer H.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5462879
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5462879
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3836
