Cancer with low cathepsin D levels is susceptible to vacuolar (H+)‐ATPase inhibition
Cancer with low cathepsin D levels is susceptible to vacuolar (H+)‐ATPase inhibition
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Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
Vacuolar (H+)‐ATPases (V‐ATPases) have important roles in the supply of nutrients to tumors by mediating autophagy and the endocytic uptake of extracellular fluids. Accordingly, V‐ATPases are attractive therapeutic targets for cancer. However, the clinical use of V‐ATPase inhibitors as anticancer drugs has not been realized, possibly owing to their...
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Full title
Cancer with low cathepsin D levels is susceptible to vacuolar (H+)‐ATPase inhibition
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480082
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480082
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.13240
