Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape
Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape
About this item
Full title
Author / Creator
Chen, Zhaoyi , Chang, Wing Y. , Etheridge, Alton , Strickfaden, Hilmar , Jin, Zhigang , Palidwor, Gareth , Cho, Ji‐Hoon , Wang, Kai , Kwon, Sarah Y. , Doré, Carole , Raymond, Angela , Hotta, Akitsu , Ellis, James , Kandel, Rita A. , Dilworth, F. Jeffrey , Perkins, Theodore J. , Hendzel, Michael J. , Galas, David J. and Stanford, William L.
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Summary
Ideally, disease modeling using patient‐derived induced pluripotent stem cells (iPSCs) enables analysis of disease initiation and progression. This requires any pathological features of the patient cells used for reprogramming to be eliminated during iPSC generation. Hutchinson–Gilford progeria syndrome (HGPS) is a segmental premature ag...
Alternative Titles
Full title
Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape
Authors, Artists and Contributors
Author / Creator
Chang, Wing Y.
Etheridge, Alton
Strickfaden, Hilmar
Jin, Zhigang
Palidwor, Gareth
Cho, Ji‐Hoon
Wang, Kai
Kwon, Sarah Y.
Doré, Carole
Raymond, Angela
Hotta, Akitsu
Ellis, James
Kandel, Rita A.
Dilworth, F. Jeffrey
Perkins, Theodore J.
Hendzel, Michael J.
Galas, David J.
Stanford, William L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5506428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5506428
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12621