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Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape

Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5506428

Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape

About this item

Full title

Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2017-08, Vol.16 (4), p.870-887

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Summary
Ideally, disease modeling using patient‐derived induced pluripotent stem cells (iPSCs) enables analysis of disease initiation and progression. This requires any pathological features of the patient cells used for reprogramming to be eliminated during iPSC generation. Hutchinson–Gilford progeria syndrome (HGPS) is a segmental premature ag...

Alternative Titles

Full title

Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5506428

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5506428

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.12621

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