Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Key Points
Cancer cells display high aerobic glycolysis despite oxidative phosphorylation.
High aerobic glycolysis distinguishes cancer cells from normal cells, and is exploited to detect tumours
in vivo
.
Cancer cells increase glucose flux to meet anabolic demands and to maintain the redox state.
Cancer cells preferentially expre...
Alternative Titles
Full title
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5516800
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5516800
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc.2016.77
