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The chemical evolution of oligonucleotide therapies of clinical utility

The chemical evolution of oligonucleotide therapies of clinical utility

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5517098

The chemical evolution of oligonucleotide therapies of clinical utility

About this item

Full title

The chemical evolution of oligonucleotide therapies of clinical utility

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2017-03, Vol.35 (3), p.238-248

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Refinements in the chemistries employed in oligonucleotide therapeutics have galvanized clinical progress. The complex interplay between chemical modifications and integration into sequence architecture is discussed in the context of antisense and small-interfering RNA drugs.
After nearly 40 years of development, oligonucleotide therapeutics are...

Alternative Titles

Full title

The chemical evolution of oligonucleotide therapies of clinical utility

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5517098

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5517098

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.3765

How to access this item