Multiregion ultra‐deep sequencing reveals early intermixing and variable levels of intratumoral hete...
Multiregion ultra‐deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer
About this item
Full title
Author / Creator
Suzuki, Yuka , Ng, Sarah Boonhsi , Chua, Clarinda , Leow, Wei Qiang , Chng, Jermain , Liu, Shi Yang , Ramnarayanan, Kalpana , Gan, Anna , Ho, Dan Liang , Ten, Rachel , Su, Yan , Lezhava, Alexandar , Lai, Jiunn Herng , Koh, Dennis , Lim, Kiat Hon , Tan, Patrick , Rozen, Steven G. and Tan, Iain Beehuat
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Intratumor heterogeneity (ITH) contributes to cancer progression and chemoresistance. We sought to comprehensively describe ITH of somatic mutations, copy number, and transcriptomic alterations involving clinically and biologically relevant gene pathways in colorectal cancer (CRC). We performed multiregion, high‐depth (384× on average) sequencing o...
Alternative Titles
Full title
Multiregion ultra‐deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5527459
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5527459
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12012
