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Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528444

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

About this item

Full title

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

Publisher

United States: Elsevier B.V

Journal title

Molecular oncology, 2013-12, Vol.7 (6), p.1142-1151

Language

English

Formats

Publication information

Publisher

United States: Elsevier B.V

More information

Scope and Contents

Contents

CUB-domain-containing-protein-1 (CDCP1) is an integral membrane protein whose expression is up-regulated in various cancer types. Although high CDCP1 expression has been correlated with poor prognosis in lung, breast, pancreas, and renal cancer, its functional role in tumor formation or progression is incompletely understood. So far it has remained...

Alternative Titles

Full title

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528444

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528444

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1016/j.molonc.2013.08.009

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