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Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepato...

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepato...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528578

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma

About this item

Full title

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma

Publisher

United States: Elsevier B.V

Journal title

Molecular oncology, 2014-10, Vol.8 (7), p.1266-1277

Language

English

Formats

Publication information

Publisher

United States: Elsevier B.V

More information

Scope and Contents

Contents

Effective pharmacological intervention of advanced hepatocellular carcinoma (HCC) is currently lacking. Despite the use of tyrosine kinase inhibitors (TKIs) for the targeted therapy of several malignancies, no agent has been developed to specifically interfere with the oncogenic tyrosine kinase signaling aberrations found in HCC. Therefore, we adop...

Alternative Titles

Full title

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528578

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528578

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1016/j.molonc.2014.04.008

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