Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insuli...
Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response
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Author / Creator
Blasco-Baque, Vincent , Garidou, Lucile , Pomié, Céline , Escoula, Quentin , Loubieres, Pascale , Le Gall-David, Sandrine , Lemaitre, Mathieu , Nicolas, Simon , Klopp, Pascale , Waget, Aurélie , Azalbert, Vincent , Colom, André , Bonnaure-Mallet, Martine , Kemoun, Philippe , Serino, Matteo and Burcelin, Rémy
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
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Publisher
England: BMJ Publishing Group LTD
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Scope and Contents
Contents
ObjectiveTo identify a causal mechanism responsible for the enhancement of insulin resistance and hyperglycaemia following periodontitis in mice fed a fat-enriched diet.DesignWe set-up a unique animal model of periodontitis in C57Bl/6 female mice by infecting the periodontal tissue with specific and alive pathogens like Porphyromonas gingivalis (Pg...
Alternative Titles
Full title
Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531227
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531227
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2015-309897