Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to...
Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury
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Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Contents
ObjectiveLiver fibrosis is associated with significant collagen-I deposition largely produced by activated hepatic stellate cells (HSCs); yet, the link between hepatocyte damage and the HSC profibrogenic response remains unclear. Here we show significant induction of osteopontin (OPN) and high-mobility group box-1 (HMGB1) in liver fibrosis. Since O...
Alternative Titles
Full title
Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5532463
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5532463
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2015-310752
