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The Cα-H···O Hydrogen Bond: A Determinant of Stability and Specificity in Transmembrane Helix Intera...

The Cα-H···O Hydrogen Bond: A Determinant of Stability and Specificity in Transmembrane Helix Intera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_55372

The Cα-H···O Hydrogen Bond: A Determinant of Stability and Specificity in Transmembrane Helix Interactions

About this item

Full title

The Cα-H···O Hydrogen Bond: A Determinant of Stability and Specificity in Transmembrane Helix Interactions

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (16), p.9056-9061

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

The Cα-H···O hydrogen bond has been given little attention as a determinant of transmembrane helix association. Stimulated by recent calculations suggesting that such bonds can be much stronger than has been supposed, we have analyzed 11 known membrane protein structures and found that apparent carbon α hydrogen bonds cluster frequently at glycine-...

Alternative Titles

Full title

The Cα-H···O Hydrogen Bond: A Determinant of Stability and Specificity in Transmembrane Helix Interactions

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_55372

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_55372

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.161280798

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