Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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United States: American Association for the Advancement of Science
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Contents
Aerobic glycolysis (the Warburg effect) is a metabolic hallmark of activated T cells and has been implicated in augmenting effector T cell responses, including expression f of the proinflammatory cytokine interferon-γ (IFN-γ), via 3 untranslated region (3'UTR)-mediated mechanisms. Here, we show that lactate dehydrogenase A (LDHA) is induced in acti...
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Full title
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5539971
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5539971
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaf6284
