Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
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Author / Creator
Howson, Joanna M M , Zhao, Wei , Barnes, Daniel R , Ho, Weang-Kee , Young, Robin , Paul, Dirk S , Waite, Lindsay L , Freitag, Daniel F , Fauman, Eric B , Salfati, Elias L , Sun, Benjamin B , Eicher, John D , Johnson, Andrew D , Sheu, Wayne H H , Nielsen, Sune F , Lin, Wei-Yu , Surendran, Praveen , Malarstig, Anders , Wilk, Jemma B , Tybjærg-Hansen, Anne , Rasmussen, Katrine L , Kamstrup, Pia R , Deloukas, Panos , Erdmann, Jeanette , Kathiresan, Sekar , Samani, Nilesh J , Schunkert, Heribert , Watkins, Hugh , Do, Ron , Rader, Daniel J , Johnson, Julie A , Hazen, Stanley L , Quyyumi, Arshed A , Spertus, John A , Pepine, Carl J , Franceschini, Nora , Justice, Anne , Reiner, Alex P , Buyske, Steven , Hindorff, Lucia A , Carty, Cara L , North, Kari E , Kooperberg, Charles , Boerwinkle, Eric , Young, Kristin , Graff, Mariaelisa , Peters, Ulrike , Absher, Devin , Hsiung, Chao A , Lee, Wen-Jane , Taylor, Kent D , Chen, Ying-Hsiang , Lee, I-Te , Guo, Xiuqing , Chung, Ren-Hua , Hung, Yi-Jen , Rotter, Jerome I , Juang, Jyh-Ming J , Quertermous, Thomas , Wang, Tzung-Dau , Rasheed, Asif , Frossard, Philippe , Alam, Dewan S , Majumder, Abdulla al Shafi , Di Angelantonio, Emanuele , Chowdhury, Rajiv , Chen, Yii-Der Ida , Nordestgaard, Børge G , Assimes, Themistocles L , Danesh, John , Butterworth, Adam S , Saleheen, Danish , EPIC-CVD and CARDIoGRAMplusC4D
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Joanna Howson and colleagues perform a genome-wide association study and meta-analysis for coronary artery disease in large, trans-ancestry cohorts. They identify 15 new loci and correlate these regions with cell-type-specific gene expression and plasma protein levels to find novel pathways and potential mechanisms of disease.
Coronary artery di...
Alternative Titles
Full title
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Authors, Artists and Contributors
Author / Creator
Zhao, Wei
Barnes, Daniel R
Ho, Weang-Kee
Young, Robin
Paul, Dirk S
Waite, Lindsay L
Freitag, Daniel F
Fauman, Eric B
Salfati, Elias L
Sun, Benjamin B
Eicher, John D
Johnson, Andrew D
Sheu, Wayne H H
Nielsen, Sune F
Lin, Wei-Yu
Surendran, Praveen
Malarstig, Anders
Wilk, Jemma B
Tybjærg-Hansen, Anne
Rasmussen, Katrine L
Kamstrup, Pia R
Deloukas, Panos
Erdmann, Jeanette
Kathiresan, Sekar
Samani, Nilesh J
Schunkert, Heribert
Watkins, Hugh
Do, Ron
Rader, Daniel J
Johnson, Julie A
Hazen, Stanley L
Quyyumi, Arshed A
Spertus, John A
Pepine, Carl J
Franceschini, Nora
Justice, Anne
Reiner, Alex P
Buyske, Steven
Hindorff, Lucia A
Carty, Cara L
North, Kari E
Kooperberg, Charles
Boerwinkle, Eric
Young, Kristin
Graff, Mariaelisa
Peters, Ulrike
Absher, Devin
Hsiung, Chao A
Lee, Wen-Jane
Taylor, Kent D
Chen, Ying-Hsiang
Lee, I-Te
Guo, Xiuqing
Chung, Ren-Hua
Hung, Yi-Jen
Rotter, Jerome I
Juang, Jyh-Ming J
Quertermous, Thomas
Wang, Tzung-Dau
Rasheed, Asif
Frossard, Philippe
Alam, Dewan S
Majumder, Abdulla al Shafi
Di Angelantonio, Emanuele
Chowdhury, Rajiv
Chen, Yii-Der Ida
Nordestgaard, Børge G
Assimes, Themistocles L
Danesh, John
Butterworth, Adam S
Saleheen, Danish
EPIC-CVD
CARDIoGRAMplusC4D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5555387
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5555387
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/ng.3874
