Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Jonathan Cohen, Helen Hobbs and colleagues show that adiposity significantly amplifies the effects of
PNPLA3
,
TM6SF2
, and
GCKR
sequence variants on nonalcoholic fatty liver disease. They find that synergy between adiposity and genotype influences the full spectrum of the disease, from steatosis to hepatic inflammation and cirrho...
Alternative Titles
Full title
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5562020
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5562020
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3855
