Echinacoside Protects Against MPP+-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation
Echinacoside Protects Against MPP+-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation
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Author / Creator
Zhao, Qing , Yang, Xiaoyan , Cai, Dingfang , Ye, Ling , Hou, Yuqing , Zhang, Lijun , Cheng, Jiwei , Shen, Yuan , Wang, Kaizhe and Bai, Yu
Publisher
Singapore: Springer Singapore
Journal title
Language
English
Formats
Publication information
Publisher
Singapore: Springer Singapore
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Scope and Contents
Contents
Echinacoside (ECH) is protective in a mouse model of Parkinson' s disease (PD) induced by 1-methyl-4- phenylpyridinium ion (MPP+). To investigate the mechanisms involved, SH-SYSY neuroblastoma ceils were treated with MPP+ or a combination of MPP+ and ECH, and the expression of ATF3 (activating transcription factor 3), CHOP (C/EBP-homologous protein...
Alternative Titles
Full title
Echinacoside Protects Against MPP+-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5563786
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5563786
Other Identifiers
ISSN
1673-7067
E-ISSN
1995-8218
DOI
10.1007/s12264-016-0047-4