Generation of pure GABAergic neurons by transcription factor programming
Generation of pure GABAergic neurons by transcription factor programming
About this item
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Author / Creator
Yang, Nan , Chanda, Soham , Marro, Samuele , Ng, Yi-Han , Janas, Justyna A , Haag, Daniel , Ang, Cheen Euong , Tang, Yunshuo , Flores, Quetzal , Mall, Moritz , Wapinski, Orly , Li, Mavis , Ahlenius, Henrik , Rubenstein, John L , Chang, Howard Y , Buylla, Arturo Alvarez , Südhof, Thomas C and Wernig, Marius
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Transient transcription factor expression rapidly induces a homogenous population of mature GABAergic neurons from human pluripotent stem cells, aiding the study of inhibitory neuron function and disease.
Approaches to differentiating pluripotent stem cells (PSCs) into neurons currently face two major challenges—(i) generated cells are immature,...
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Full title
Generation of pure GABAergic neurons by transcription factor programming
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5567689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5567689
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.4291
