Exposure–response relationship of ramucirumab in patients with advanced second-line colorectal cance...
Exposure–response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial
About this item
Full title
Author / Creator
Cohn, Allen Lee , Yoshino, Takayuki , Heinemann, Volker , Obermannova, Radka , Bodoky, György , Prausová, Jana , Garcia-Carbonero, Rocio , Ciuleanu, Tudor , Garcia-Alfonso, Pilar , Portnoy, David C. , Van Cutsem, Eric , Yamazaki, Kentaro , Clingan, Philip R. , Polikoff, Jonathon , Lonardi, Sara , O’Brien, Lisa M. , Gao, Ling , Yang, Ling , Ferry, David , Nasroulah, Federico and Tabernero, Josep
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Purpose
To characterize ramucirumab exposure–response relationships for efficacy and safety in patients with metastatic colorectal cancer (mCRC) using data from the RAISE study.
Methods
Sparse pharmacokinetic samples were collected; a population pharmacokinetic analysis was conducted. Univariate and multivariate Cox proportional hazards mo...
Alternative Titles
Full title
Exposure–response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial
Authors, Artists and Contributors
Author / Creator
Yoshino, Takayuki
Heinemann, Volker
Obermannova, Radka
Bodoky, György
Prausová, Jana
Garcia-Carbonero, Rocio
Ciuleanu, Tudor
Garcia-Alfonso, Pilar
Portnoy, David C.
Van Cutsem, Eric
Yamazaki, Kentaro
Clingan, Philip R.
Polikoff, Jonathon
Lonardi, Sara
O’Brien, Lisa M.
Gao, Ling
Yang, Ling
Ferry, David
Nasroulah, Federico
Tabernero, Josep
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5573752
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5573752
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-017-3380-z
