Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
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Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publisher
United States: Massachusetts Medical Society
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Scope and Contents
Contents
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
The pathway consisting of the receptor programmed cell death 1 (PD-1; also called CD279) and its ligands, PD-L...
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Full title
Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5575761
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5575761
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMra1514296
