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Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5575761

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

About this item

Full title

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

Author / Creator

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2016-11, Vol.375 (18), p.1767-1778

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
The pathway consisting of the receptor programmed cell death 1 (PD-1; also called CD279) and its ligands, PD-L...

Alternative Titles

Full title

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5575761

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5575761

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMra1514296

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