ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
About this item
Full title
Author / Creator
The International SU2C/PCF Prostate Cancer Dream Team , International SU2C/PCF Prostate Cancer Dream Team , Bose, Rohit , Karthaus, Wouter R. , Armenia, Joshua , Abida, Wassim , Iaquinta, Phillip J. , Zhang, Zeda , Wongvipat, John , Wasmuth, Elizabeth V. , Shah, Neel , Sullivan, Patrick S. , Doran, Michael G. , Wang, Ping , Patruno, Anna , Zhao, Yilin , Zheng, Deyou , Schultz, Nikolaus and Sawyers, Charles L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
In prostate cancer, the oncogenicity of transcription factor ERG is mediated, in part, by competition with another member of the ETS family, ERF.
Opposing protein actions in tumour growth
In prostate cancer,
TMPRSS2
–
ERG
translocations are very frequent and lead to overexpression of ERG, which can trigger tumour growth. Rohit Bos...
Alternative Titles
Full title
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
Authors, Artists and Contributors
Author / Creator
International SU2C/PCF Prostate Cancer Dream Team
Bose, Rohit
Karthaus, Wouter R.
Armenia, Joshua
Abida, Wassim
Iaquinta, Phillip J.
Zhang, Zeda
Wongvipat, John
Wasmuth, Elizabeth V.
Shah, Neel
Sullivan, Patrick S.
Doran, Michael G.
Wang, Ping
Patruno, Anna
Zhao, Yilin
Zheng, Deyou
Schultz, Nikolaus
Sawyers, Charles L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5576182
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5576182
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22820
