Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The CRISPR-associated bacterial enzyme C2c2 is shown to contain two separable, distinct sites for the highly sensitive detection and cleavage of single-stranded RNA.
The RNA cleaving enzyme C2c2
The programmed sequence-specific cleavage of RNA and DNA by CRISPR-associated enzymes has revolutionized genome editing. An alternative to canonical...
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Full title
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5576363
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5576363
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19802
