Protective immunity differs between routes of administration of attenuated malaria parasites indepen...
Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In humans and murine models of malaria, intradermal immunization (ID-I) with genetically attenuated sporozoites that arrest in liver induces lower protective immunity than intravenous immunization (IV-I). It is unclear whether this difference is caused by fewer sporozoites migrating into the liver or by suboptimal hepatic and injection site-depende...
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Full title
Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5583236
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5583236
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-10480-1
