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An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5589491

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

About this item

Full title

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2017-09, Vol.24 (9), p.752-757

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Antimicrobial peptide Api137 inhibits translation by trapping release factors 1 or 2 associated with ribosomes and arresting termination.
Many antibiotics stop bacterial growth by inhibiting different steps of protein synthesis. However, no specific inhibitors of translation termination are known. Proline-rich antimicrobial peptides, a component...

Alternative Titles

Full title

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5589491

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5589491

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.3439

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