Log in to save to my catalogue

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin...

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595883

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes)

About this item

Full title

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes)

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-09, Vol.7 (1), p.11435-13, Article 11435

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Myostatin (MSTN) suppresses skeletal muscle development and growth in mammals, but its role in fish is less well understood. Here we used CRISPR/Cas9 to mutate the MSTN gene in medaka (
Oryzias latipes
) and evaluate subsequent growth performance. We produced mutant F0 fish that carried different frameshifts in the
Ol
MSTN coding sequen...

Alternative Titles

Full title

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595883

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595883

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-09966-9

How to access this item