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A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing co...

A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5623180

A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy

About this item

Full title

A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy

Publisher

New York: Nature Publishing Group US

Journal title

Laboratory investigation, 2017-10, Vol.97 (10), p.1245-1261

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

DCLK1 expression is critically required for maintaining growth of human colon cancer cells (hCCCs). Human colorectal tumors (CRCs) and hCCCs express a novel short isoform of DCLK1 (DCLK1-S; isoform 2) from
β
-promoter of h
DCLK1
gene, while normal colons express long isoform (DCLK1-L; isoform 1) from 5′(
α
)-promoter, suggesting t...

Alternative Titles

Full title

A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5623180

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5623180

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2017.40

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