A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing co...
A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy
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Full title
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
DCLK1 expression is critically required for maintaining growth of human colon cancer cells (hCCCs). Human colorectal tumors (CRCs) and hCCCs express a novel short isoform of DCLK1 (DCLK1-S; isoform 2) from
β
-promoter of h
DCLK1
gene, while normal colons express long isoform (DCLK1-L; isoform 1) from 5′(
α
)-promoter, suggesting t...
Alternative Titles
Full title
A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5623180
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5623180
Other Identifiers
ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/labinvest.2017.40