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HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mec...

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5634422

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

About this item

Full title

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-10, Vol.7 (1), p.12866-16, Article 12866

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

While HIV kills most of the cells it infects, a small number of infected cells survive and become latent viral reservoirs, posing a significant barrier to HIV eradication. However, the mechanism by which immune cells resist HIV-induced apoptosis is still incompletely understood. Here, we demonstrate that while acute HIV infection of human microglia...

Alternative Titles

Full title

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5634422

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5634422

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-12758-w

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