Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
About this item
Full title
Author / Creator
Yan, Kelley S. , Janda, Claudia Y. , Chang, Junlei , Zheng, Grace X. Y. , Larkin, Kathryn A. , Luca, Vincent C. , Chia, Luis A. , Mah, Amanda T. , Han, Arnold , Terry, Jessica M. , Ootani, Akifumi , Roelf, Kelly , Lee, Mark , Yuan, Jenny , Li, Xiao , Bolen, Christopher R. , Wilhelmy, Julie , Davies, Paige S. , Ueno, Hiroo , von Furstenberg, Richard J. , Belgrader, Phillip , Ziraldo, Solongo B. , Ordonez, Heather , Henning, Susan J. , Wong, Melissa H. , Snyder, Michael P. , Weissman, Irving L. , Hsueh, Aaron J. , Mikkelsen, Tarjei S. , Garcia, K. Christopher and Kuo, Calvin J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
R-spondin and Wnt ligand families act non-redundantly and cooperatively within the same molecular pathway in the intestinal stem-cell niche to maintain stem-cell competency and drive stem-cell expansion.
Roles of Wnt and R-Spondin in the intestine
Wnt ligands interact with FZD and Lrp5/6-type receptors to influence diverse developmental, home...
Alternative Titles
Full title
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
Authors, Artists and Contributors
Author / Creator
Janda, Claudia Y.
Chang, Junlei
Zheng, Grace X. Y.
Larkin, Kathryn A.
Luca, Vincent C.
Chia, Luis A.
Mah, Amanda T.
Han, Arnold
Terry, Jessica M.
Ootani, Akifumi
Roelf, Kelly
Lee, Mark
Yuan, Jenny
Li, Xiao
Bolen, Christopher R.
Wilhelmy, Julie
Davies, Paige S.
Ueno, Hiroo
von Furstenberg, Richard J.
Belgrader, Phillip
Ziraldo, Solongo B.
Ordonez, Heather
Henning, Susan J.
Wong, Melissa H.
Snyder, Michael P.
Weissman, Irving L.
Hsueh, Aaron J.
Mikkelsen, Tarjei S.
Garcia, K. Christopher
Kuo, Calvin J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5641471
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5641471
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22313
