Log in to save to my catalogue

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood...

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5642679

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

About this item

Full title

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.E8675-E8684

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

It has been known for some time that atherosclerotic lesions preferentially develop in areas exposed to lowSS and are characterized by a proinflammatory, apoptotic, and senescent endothelial phenotype. Conversely, areas exposed to high SS are protected from plaque development, but the mechanisms have remained elusive. Autophagy is a protective mech...

Alternative Titles

Full title

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5642679

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5642679

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1702223114

How to access this item