Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to p...
Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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United States: National Academy of Sciences
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Contents
C4a is a small protein released from complement component C4 upon activation of the complement system’s classical and lectin pathways, which are important constituents of innate immune surveillance. Despite the structural similarity between C4a and well-described anaphylatoxins C3a and C5a, the binding partner and biological function of C4a have re...
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Full title
Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5642699
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5642699
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1707364114
