Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multip...
Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple Sclerosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Herein, we have used bioinformatics tools to predict five clusters defining ligand-binding sites on the extracellular domain of human CD300b receptor, presumably involved in the formation of both homodimers and heterodimers with other CD300 family members. Site-directed mutagenesis revealed residues glutamic acid 28 and glutamine 29 in cluster 5 to...
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Effect of Specific Mutations in Cd300 Complexes Formation; Potential Implication of Cd300f in Multiple Sclerosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5648872
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5648872
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-12881-8