A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Site-specific localization is critical for improving the therapeutic efficacy and safety of drugs. Nanoparticles have emerged as promising tools for localized drug delivery. However, over 90% of systemically injected nanocarriers typically accumulate in the liver and spleen due to resident macrophages that form the mononuclear phagocyte system. In...
Alternative Titles
Full title
A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5653759
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5653759
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-14221-2
