Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon m...
Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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PROPPINs (β-propellers that bind polyphosphoinositides) are PtdIns3P and PtdIns(3,5)P
2
binding autophagy related proteins. They contain two phosphatidylinositolphosphate (PIP) binding sites and a conserved FRRG motif is essential for PIP binding. Here we present the 2.0 Å resolution crystal structure of the PROPPIN Atg18 from
Pichia angus...
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Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5656675
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5656675
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-14337-5