Direct, enantioselective α-alkylation of aldehydes using simple olefins
Direct, enantioselective α-alkylation of aldehydes using simple olefins
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although the α-alkylation of ketones has already been established, the analogous reaction using aldehyde substrates has proven surprisingly elusive. Despite the structural similarities between the two classes of compounds, the sensitivity and unique reactivity of the aldehyde functionality has typically required activated substrates or specialized...
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Direct, enantioselective α-alkylation of aldehydes using simple olefins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5665178
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5665178
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2797
