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ZnT3 Gene Deletion Reduces Colchicine-Induced Dentate Granule Cell Degeneration

ZnT3 Gene Deletion Reduces Colchicine-Induced Dentate Granule Cell Degeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5666870

ZnT3 Gene Deletion Reduces Colchicine-Induced Dentate Granule Cell Degeneration

About this item

Full title

ZnT3 Gene Deletion Reduces Colchicine-Induced Dentate Granule Cell Degeneration

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2017-10, Vol.18 (10), p.2189

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Our previous study demonstrated that colchicine-induced dentate granule cell death is caused by blocking axonal flow and the accumulation of intracellular zinc. Zinc is concentrated in the synaptic vesicles via zinc transporter 3 (
), which facilitates zinc transport from the cytosol into the synaptic vesicles. The aim of the present study was t...

Alternative Titles

Full title

ZnT3 Gene Deletion Reduces Colchicine-Induced Dentate Granule Cell Degeneration

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5666870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5666870

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms18102189

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