A vital sugar code for ricin toxicity
A vital sugar code for ricin toxicity
About this item
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Author / Creator
Taubenschmid, Jasmin , Stadlmann, Johannes , Jost, Markus , Klokk, Tove Irene , Rillahan, Cory D , Leibbrandt, Andreas , Mechtler, Karl , Paulson, James C , Jude, Julian , Zuber, Johannes , Sandvig, Kirsten , Elling, Ulrich , Marquardt, Thorsten , Thiel, Christian , Koerner, Christian and Penninger, Josef M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Ricin is one of the most feared bioweapons in the world due to its extreme toxicity and easy access. Since no anti- dote exists, it is of paramount importance to identify the pathways underlying ricin toxicity. Here, we demonstrate that the Golgi GDP-fucose transporter S1c35cl and fucosyltransferase Fut9 are key regulators of ricin toxicity. Ge- ne...
Alternative Titles
Full title
A vital sugar code for ricin toxicity
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674155
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674155
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2017.116