Recurrent activating mutations of CD28 in peripheral T-cell lymphomas
Recurrent activating mutations of CD28 in peripheral T-cell lymphomas
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Author / Creator
Rohr, J , Guo, S , Huo, J , Bouska, A , Lachel, C , Li, Y , Simone, P D , Zhang, W , Gong, Q , Wang, C , Cannon, A , Heavican, T , Mottok, A , Hung, S , Rosenwald, A , Gascoyne, R , Fu, K , Greiner, T C , Weisenburger, D D , Vose, J M , Staudt, L M , Xiao, W , Borgstahl, G E O , Davis, S , Steidl, C , McKeithan, T , Iqbal, J and Chan, W C
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T-cell neoplasms with a poor prognosis. Recently, mutations in TET2 and other epigenetic modifiers as well as RHOA have been identified in these diseases, particularly in angioimmunoblastic T-cell lymphoma (AITL). CD28 is the major co-stimulatory receptor in T cells which,...
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Full title
Recurrent activating mutations of CD28 in peripheral T-cell lymphomas
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5688878
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5688878
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2015.357
