Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA...
Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease
About this item
Full title
Author / Creator
Mano, Tatsuo , Nagata, Kenichi , Nonaka, Takashi , Tarutani, Airi , Imamura, Tomohiro , Hashimoto, Tadafumi , Bannai, Taro , Koshi-Mano, Kagari , Tsuchida, Takeyuki , Ohtomo, Ryo , Takahashi-Fujigasaki, Junko , Yamashita, Satoshi , Ohyagi, Yasumasa , Yamasaki, Ryo , Tsuji, Shoji , Tamaoka, Akira , Ikeuchi, Takeshi , Saido, Takaomi C. , Iwatsubo, Takeshi , Ushijima, Toshikazu , Murayama, Shigeo , Hasegawa, Masato and Iwata, Atsushi
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by pathology of accumulated amyloid β (Aβ) and phosphorylated tau proteins in the brain. Postmortem degradation and cellular complexity within the brain have limited approaches to molecularly define the causal relationship between pathological features and neuronal dysfun...
Alternative Titles
Full title
Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Nagata, Kenichi
Nonaka, Takashi
Tarutani, Airi
Imamura, Tomohiro
Hashimoto, Tadafumi
Bannai, Taro
Koshi-Mano, Kagari
Tsuchida, Takeyuki
Ohtomo, Ryo
Takahashi-Fujigasaki, Junko
Yamashita, Satoshi
Ohyagi, Yasumasa
Yamasaki, Ryo
Tsuji, Shoji
Tamaoka, Akira
Ikeuchi, Takeshi
Saido, Takaomi C.
Iwatsubo, Takeshi
Ushijima, Toshikazu
Murayama, Shigeo
Hasegawa, Masato
Iwata, Atsushi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5692545
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5692545
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1707151114
