Large-scale epigenomic reprogramming during pancreatic cancer progression links anabolic glucose met...
Large-scale epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
About this item
Full title
Author / Creator
McDonald, Oliver G. , Li, Xin , Saunders, Tyler , Tryggvadottir, Rakel , Mentch, Samantha J. , Warmoes, Marc O. , Word, Anna E. , Carrer, Alessandro , Salz, Tal H. , Natsume, Sonoko , Stauffer, Kimberly M. , Makohon-Moore, Alvin , Zhong, Yi , Wu, Hao , Wellen, Kathryn E. , Locasale, Jason W. , Iacobuzio-Donahue, Christine and Feinberg, Andrew P.
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
During the evolutionary progression of pancreatic ductal adenocarcinoma (PDAC), heterogeneous subclonal populations emerge that drive primary tumor growth, regional spread, distant metastasis, and patient death
1
–
3
. However, the genetics of metastases largely reflects that of the primary tumor in untreated patients, and PDAC driver m...
Alternative Titles
Full title
Large-scale epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
Authors, Artists and Contributors
Author / Creator
Li, Xin
Saunders, Tyler
Tryggvadottir, Rakel
Mentch, Samantha J.
Warmoes, Marc O.
Word, Anna E.
Carrer, Alessandro
Salz, Tal H.
Natsume, Sonoko
Stauffer, Kimberly M.
Makohon-Moore, Alvin
Zhong, Yi
Wu, Hao
Wellen, Kathryn E.
Locasale, Jason W.
Iacobuzio-Donahue, Christine
Feinberg, Andrew P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5695682
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5695682
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3753
