Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells
Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells
About this item
Full title
Author / Creator
Hu, Junping , Wang, Weili , Zhang, Fan , Li, Pin-Lan , Boini, Krishna M. , Yi, Fan and Li, Ningjun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Proteinuria is closely associated with the progression of chronic kidney diseases (CKD) by producing renal tubulointerstitial fibrosis. Over-activation of hypoxia inducible factor (HIF)-1α has been implicated in the progression of CKD. The present study tested the hypothesis that HIF-1α mediates albumin-induced profibrotic effect in cultured renal...
Alternative Titles
Full title
Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5696482
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5696482
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-15972-8
