Up‐regulation of golgi α‐mannosidase IA and down‐regulation of golgi α‐mannosidase IC activates unfo...
Up‐regulation of golgi α‐mannosidase IA and down‐regulation of golgi α‐mannosidase IC activates unfolded protein response during hepatocarcinogenesis
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United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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Language
English
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Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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Contents
α‐1,2 mannosidases, key enzymes in N‐glycosylation, are required for the formation of mature glycoproteins in eukaryotes. Aberrant regulation of α‐1,2 mannosidases can result in cancer, although the underlying mechanisms are unclear. Here, we report the distinct roles of α‐1,2 mannosidase subtypes (MAN1A, MAN1B, ERMAN1, MAN1C) in the formation of h...
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Full title
Up‐regulation of golgi α‐mannosidase IA and down‐regulation of golgi α‐mannosidase IC activates unfolded protein response during hepatocarcinogenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5721452
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5721452
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ISSN
2471-254X
E-ISSN
2471-254X
DOI
10.1002/hep4.1032