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Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722201

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

About this item

Full title

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

Publisher

New York: Nature Publishing Group US

Journal title

Nature Medicine, 2017-12, Vol.23 (12), p.1424-1435

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Tumor organoids derived from the most common subtypes of primary liver cancer recapitulate the histologic and molecular features of the tissues of origin, even after long-term culture. These
in vitro
models, as well as those for colorectal cancer reported in Crespo
et al.
in a previous issue, are amenable for drug screening and allow th...

Alternative Titles

Full title

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722201

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722201

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X,1744-7933

DOI

10.1038/nm.4438

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