Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration
About this item
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Author / Creator
Patterson, Michaela , Barske, Lindsey , Van Handel, Ben , Rau, Christoph D , Gan, Peiheng , Sharma, Avneesh , Parikh, Shan , Denholtz, Matt , Huang, Ying , Yamaguchi, Yukiko , Shen, Hua , Allayee, Hooman , Crump, J Gage , Force, Thomas I , Lien, Ching-Ling , Makita, Takako , Lusis, Aldons J , Kumar, S Ram and Sucov, Henry M
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Henry Sucov and colleagues demonstrate substantial natural variation in the capacity of the mouse heart to regenerate after injury and link this to the prevalence of mononuclear diploid cardiomyocytes. They identify
Tnni3k
as one gene that contributes to the observed variation and validate its role through mouse knockout and zebrafish overexp...
Alternative Titles
Full title
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5736145
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5736145
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3929
